Toxaphene lethal

Toxaphene has been found to be genotoxic in a number of assays. It was mutagenic in Sal-Ttimella typhimurium, and increased the frequency of sister chromatid exchanges in cell culture. In one study toxaphene-exposed individuals had a higher incidence of chromosomal aberrations in lymphocytes than controls. However, in vivo toxaphene did not bind to DNA or produce dominant lethal mutations. ... 

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