Total Synthesis of Several Natural Epoxy Cembrenoids

3 Total Synthesis of Several Natural Epoxy Cembrenoids [Pg.277]

Reagents and Conditions (a) i. K2CO3, MeOH ii. PCC, CH2CI2 (b) TiCVZn, THE, reflux, 25 h. [Pg.278]

R = CH2OH, Pseudoplexaurol (182) R = CHO, Pseudoplexaural (183) R = C02Me, Pseudoplexauric acid methyl ester (184) [Pg.279]

Stereoselective construction of the epoxide functionality in the macrocyclic cembrene skeleton comprises a challenging task for total synthesis. We report herein the completion of the total syntheses of the above cembranoxides in detail. [Pg.281]

A concise and efficient enantioselective synthesis of (+)-(115,125)-epoxysarcophytol-A (181) was accomplished for the first time in six simple operations from readily [Pg.281]

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