Tolypocladium species

RM Wenger. Synthesis of cyclosporine. Total synthesis of cyclosporin A and cyclosporin H, two fungal metabolites isolated from the species Tolypocladium infla-tum Gams. Helv Chim Acta 67, 502, 1984. 

Immunosuppressant produced as a metabolite by the fungus species Beauvaria nivea Gams Tolypocladium inflatum Gams ... 

The species is obviously very similar to Tolypocladium and Haptocillium, but differs from them in vitro by forming single, swollen phialides supported by slender stalks. Plesiospora globosa was found in nematodes in forest detritus in Wisconsin. The fungus was also observed in Canada by Barron (1978), in Apsheron, Azerbaidzhan, by Shilova (1987) and in Japan and Illinois by S. L. Glocking (personal communication, 2002). 

Goettel et al., 1984 Couch et al., 1974) C. parasiticus parasitizes rotifers (Bissett, 1983). The latter species was transferred from Tolypocladium by Sigler et al. (1987), and indeed the two genera are very similar. C. clavisporus has been considered as a potential biocontrol of mosquito larvae in aquatic habitats (Sweeney et al., 1973). 

Type species Tolypocladium inflatum W. Gams, nom. cons. 

Samson RA, Soares GG Jr. Entomopathogenic species of the hyphomycete genus Tolypocladium. J Invertbr Pathol 43 133-139, 1984. 

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