Tissues nonmineralized

Intramembranous ossification is responsible for most of the mineralization of the skull, including the maxilla and mandible. It begins with the differentiation and activation of osteoblasts from fibroblast-related precursors within a region of connective tissue that demarcates where the bone will develop. The osteoblasts secrete a nonmineralized protein-rich (osteoid) matrix and, as they move away, the matrix mineralizes (Fig. 9.3a). The periosteum remains uncalcified and contains latent and undifferentiated osteoblasts for bone remodeling. Odontoblasts (Ob) and cementoblasts secrete an osteoid-like matrix similar to that of intramembraneous ossification. 

TABLE 43.4 Mechanical Properties of Some Nonmineralized Human Tissues... 

Katz, E.P. and Li, S.T. 1972. The molecular organization of collagen in mineralized and nonmineralized tissues. Biochem. Biophys. Res. Commun. 3 1368-1373. 

Nonlinear ionic channels conductance, 28-8 Nonmineralized human tissues, mechanical properties,... 

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