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Tissue engineering scaffolds case study

Case study collagen/PCL bicomponent nanofiber scaffolds for engineering bone tissues... [Pg.255]

Physical mixtures have also been of interest to scientists working in tissue engineering. In this case, the matrix material and the drug are mixed in the soHd state and subsequently processed into porous cell carriers. This process has been used by Shea et al. [226] to load PLGA scaffolds with plasmid DNA. For their studies, they used PLGA granules and suspended them in an aqueous solution of plasmid DNA at pH 7.4 in 10 M HEPES buffer containing mannitol, which was used as a lyophilization constituent. After... [Pg.672]

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