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Tissue damage, rats, biological

As new compounds, very limited research has been done to evaluate the biological effects of ionic liquids. The topical effect of [EMIM]C1/A1C13 melts and [EMIMjCl on the integument of laboratory rat has been investigated. The study reports that [EMIMjCl is not in itself responsible for tissue damage. However, the chloroaluminate salt can induce tissue irritation, inflammation, and necrosis, due to the presence of aluminium chloride. However, treatments for aluminium chloride and hydrochloric acid are well documented. This study needs to be expanded to the other ionic liquids, and their toxicity need to be investigated [46]. [Pg.278]

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Biological tissue

Tissue damage

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