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Time Course of Drug Plasma Levels during Irregular Intake B

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The time required to reach steady-state accumulation during multiple constant dosing depends on the rate of elimination. As a rule of thumb, a plateau is reached after approximately three elimination half-lives [Pg.50]


Time Course of Drug Plasma Levels During Irregular Intake (B)... [Pg.48]




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B Plasma

During irregular intake

Irregular

Leveling courses

Plasma levels

Time course

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