Ticlopidine restenosis

Bertrand ME, Allain H, Lablanche J. A randomized trial of ticlopidine vs. placebo for prevention of acute closure and restenosis after PTCA The TACT study. Circulation 1990 82 190. 

White C, Chaitman B, Knudtson M, Chisholm R. Antiplatelet agents are effective in reducing the acute ischemic complications of angioplasty but do not prevent restenosis results from the ticlopidine trial. Coron Artery Dis 1991 2 757-767. 

Ticlopidine Only if intolerant to clopidogrel At least 250 mg bd Synergistic with aspirin in reducing platelet aggregation (6) and reducing instent restenosis (7) Concern over associated incidence of agranulocytosis (8,9), frequent gastric intolerance and skin rashes Sequential FBC required at follow-up... 

Tanabe Y Ito E, Nakagawa I, Suzuki K. Effect of cilostazol on restenosis after coronary angioplasty and stenting in comparison to conventional coronary artery stenting with ticlopidine, IntJ Cardiol 2001 78(3)285-291. 

Kamishirado H, Inoue T Mizoguchi K, et al, Randomized comparison of cilostazol versus ticlopidine hydrochloride for antiplatelet therapy after coronary stent implantation for prevention of late restenosis. Am Heart J 2002 144(2) 303—308. 

Sekiguchi M, Hoshizaki H, Adachi H, Ohshima S, Taniguchi K, Kurabayashi M, Effects of antiplatelet agents on subacute thrombosis and restenosis after successful coronary stenting A randomized comparison of ticlopidine and cilostazol. Circ J 2004 68(7) 6I0-6I4,... 

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