Thromboxane synthesis from glucose

Corey, E J, Shibasaki, M, Simple, J K, Stereocontrolled synthesis of thromboxane B2 from D-glucose, Tetrahedron Lett., 18, 1625-1626, 1977. 

Hanessian, S, LaveUee, P, Total synthesis of (4-)-thromboxane B2 from D-glucose. A detailed account. Can. J. Chem., 59, SlOSll, 1981. 

Corey, E. J., M. Shibasaki, and J. Knolle Simple Stereocontrolled Synthesis of Thromboxane B2 from Z)-Glucose. Tetrahedron Letters 1977, 1625. 

Reaction with aliyiic aicohois (1, 271-272 4, 167,5, 226-227). A key step in a recent, stereocontrolled synthesis of natural thromboxane Ba (4) from u-glucose... 

Carbohydrates have again been used as chiral precursors for the total synthesis of other natural products, including thromboxane Bj, ( —)-isoavenaciolide, and insect pheromones - but pride of place must be given to a total synthesis of (-l-)-biotin from o-glucose in which a biomimetic transformation was used in forming the tetrahydrothiophen ring (Chapter 23). 

Methyl 2,4-dideoxy-4-C-carboxymethyl-a-D-riZ o-hexopyranoside 2 -> 3 lactone (43), required as a key intermediate for the synthesis of optically active thromboxanes, has been synthesized from D-glucose by standard transformations. ... 

The au rie2Si group is used to protect in the synthesis of morphine, methynoLide from D-glucose, C+)-Aplasmomycin, thromboxane B and lOa-homothrom-boxane A, prostaglandin t d in carbapenein synthesis.3u Ph,Si protects OH in the preparation of the optically pure TriF fragment of acyl tetronic acid... 

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