Thromboembolic complications, nephrotic syndrome

Nephrotic syndrome is a life-threatening disease. Adult patients may die of thromboembolic complications and children may die of infections, and persistent nephrotic syndrome confers a substantial risk of progression to end-stage renal failure. 

Persistent nephrotic syndrome is a life-threatening disease (mainly due to the risk of thromboembolic and infectious complications) and clearly confers a high risk of progression into end-stage renal failure, which is related to the degree of proteinuria (Jl). The therapeutic goal is therefore the remission of nephrotic syndrome, or at least reduction of proteinuria. In patients with persistent nephrotic syndrome, symptomatic treatment (or prevention) of hyperlipidemia, hypercoagulability, and sodium and water retention is also warranted. 

---