Three-dimensional structure glycans

Spik, G., Coddeville, B., Mazurier, J., Bourne, Y., Cambillaut, C., and Montreuil, J. 1994a. Primary and three-dimensional structure of lactotransferrin (lactoferrin) glycans. Adv. Exp. Med. Biol. 357, 21-32. 

Currently, there is no generally accepted model for the three-dimensional structure of peptidoglycan. Two alternative models in which the glycan strands are arranged either parallel (classical model) or perpendicular ( scaffold model) to the cytoplasmic membrane are discussed [188,190]. However, the models do not need to be mutually exclusive. It may also be that the cell wall exists as a mosaic of microdomains with different structures, or perhaps new cell wall is inserted in one form before being converted to another [197]. 

Fig. 2 Three-dimensional structure of FLAP. Left panet. Monomer A is shown in ribbon representabon and in yellow, while monomer B is shown in surface representation in blue. The relative location of the active site, N-terminus, and GPI anchoring site are indicated. Right panel. Modeled structure of the GPI anchor attached to the 3D structure of PLAP. N-linked complex glycan was also modeled at N122 and at N249. This figure was kindly produced and contributed by Dr. Mark R. Wormald, Oxford Glycobiology Institute, University of Oxford, Oxford, UK...

---