Big Chemical Encyclopedia

Chemical substances, components, reactions, process design ...

Articles Figures Tables About

Three-Center Bifurcated Bonds in Proteins

The analysis of hydrogen bonds in 15 proteins recognized a number of three-center hydrogen bonds, of which 70 involve main-chain N-H, and 40 are associated with the side-chain N-H of His, Arg, Asn, Gin. Other feasible three-center bonds could be associated with hydroxyl groups of Ser, Thr, iyr but hydrogen atom positions could not be defined in these cases. [Pg.382]

Ninety percent of the three-center hydrogen bonds formed by main-chain N-H groups involve at least one protein acceptor atom the other acceptor being either a water molecule (53%) or another protein atom (47%). With side-chain N-H groups, one half interact with water molecules, the other half with one or more protein acceptors. O [Pg.382]

In future high-resolution crystal structure studies of proteins, hydrogen bonding has to be analyzed in terms of two-center and three-center interactions. It should be stressed that three-center bonds may be especially important in protein dynamics because they can be regarded as transition intermediate from one two-center bond to another (see Part IV, Chap. 25). [Pg.383]


See other pages where Three-Center Bifurcated Bonds in Proteins is mentioned: [Pg.382]   


SEARCH



Bifurcate

Bifurcated

Bond three-center

Bonded proteins

Bonding three-center bond

Bonds in proteins

Protein bonds

Proteins bonding

Three-center

© 2024 chempedia.info