Thioureas in the synthesis of heterocycles

There is an enormous literature on thiocarbonyl compounds, due in part to the technical and industrial importance of many of them, including thioamides, thioureas, xanthates, dithiocarbamates and so forth. An excellent, and recent, general review is available.107 There are also specialized reviews germane to the present chapter Griffin, Woods, and Klayman2 discussed the use of thioureas in the synthesis of heterocycles the preparation of thiazoles from thioamides is included in a three-part volume on Thiazoles 108 the use of carbon disulfide in the synthesis of trithiones and related heterocycles has been reviewed by Mayer109 and Huisgen110 has reported numerous examples of 1,3-dipolar cycloadditions in which carbon disulfide was used. 

The Molecules R2CXCR2 Including Azomethine, Carbonyl and Thiocarbonyl Ylides Their Syntheses, Properties and Reactions R. M. Kellogg, Tetrahedron, 1976,32,2165-2184. Thioureas in the Synthesis of Heterocycles T. S. Griffin, T. S. Woods and D. L. Klayman, Adv. Heterocycl. Chem., 1975,18, 100-158. 

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