Thiourea-based receptors

Abstract This review article provides a broad overview to the area of anion coordination by synthetic organic receptors and includes examples of different functional groups used to bind anions. The first section examines neutral anion receptors containing amide-, sulfonamide-, urea- and thiourea-based receptors. Then aromatics such as pyrrole, car-bazole and indole are discussed before concluding the discussion of neutral systems with examples of hydroxy OH donors. A brief overview of charged systems is also provided. 

Wu FY, Li Z, Wen ZC et al (2002) A novel thiourea-based dual fluorescent anion receptor with a rigid hydrazine spacer. Org Lett 4 3203-3205... 

Ion-Selective Electrodes based on Bis-Thiourea Receptors. Bis-thiourea derivatives 14, 15, and 17, which have a good membrane solubility, sufficient lipophilicity to prevent leaching into the aqueous sample solution, and a low tendency for self-aggregation in nonpolar solvents, were incorporated into PVC matrix liquid membranes for ISEs. While membrane electrodes based on the dibutyl derivative 14 gave a phosphate response almost identical to that of a conventional anion-exchanger electrode, a membrane electrode based on the phenyl-substituted bis-thiourea 15 exhibited a slightly improved phosphate response, which seems to be the result of improved complexation of phosphate in the sensor membrane. 

Melamine derivatives bearing thiourea and thiouronium ions have been prepared as flavin receptors <04BCJ569>. Hemolysis and cytotoxicity activities of six dendrimers based on ... 

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