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Thioridazine HCl

F Melleril (Sandoz) 1 GB Melleril (Novartis) Mellerette (Novartis) Melleril (Novartis) J Melleril (Sandoz-Sankyo) USA Thioridazine HCl (Geneva)... [Pg.2025]

The piperidine group includes mesoridazine besylate (Serentil) and thioridazine HCl (Mellaril). These produce few EPS or anti-emetic effects and can cause h5 otension. [Pg.320]

Figure 4.19 The stabilizing and lytic effects of various tranquilizers and antihistamines on human erythrocytes. Stabilization of the erythrocytes against hypotonic haemolysis is caused by butyrylperazine dimaleate, prochlorperazine ethane disulphonate, fluphenazine diHCl, reserpine phosphate, thioridazine HCl, trifluoperazine diHCl, chlorpromazine HCl, promethazine HCl, and haloperidol. High concentrations of all the compounds caused direct lysis. Stabilization by chlorpromazine sulphoxide occurred at concentrations higher than equiosmolar concentrations of NaCl or sucrose. All the compounds were dissolved in aqueous solution except haloperidol which was added to the final aqueous solution from concentrated stock ethanolic solutions. The final concentration of the erythrocytes was 2.4 x 10 cells ml A relative haemolysis of 1.0 indicates an absolute degree of haemolysis of around 40%. From Seeman and Weinstein [158] with permission. Figure 4.19 The stabilizing and lytic effects of various tranquilizers and antihistamines on human erythrocytes. Stabilization of the erythrocytes against hypotonic haemolysis is caused by butyrylperazine dimaleate, prochlorperazine ethane disulphonate, fluphenazine diHCl, reserpine phosphate, thioridazine HCl, trifluoperazine diHCl, chlorpromazine HCl, promethazine HCl, and haloperidol. High concentrations of all the compounds caused direct lysis. Stabilization by chlorpromazine sulphoxide occurred at concentrations higher than equiosmolar concentrations of NaCl or sucrose. All the compounds were dissolved in aqueous solution except haloperidol which was added to the final aqueous solution from concentrated stock ethanolic solutions. The final concentration of the erythrocytes was 2.4 x 10 cells ml A relative haemolysis of 1.0 indicates an absolute degree of haemolysis of around 40%. From Seeman and Weinstein [158] with permission.

See other pages where Thioridazine HCl is mentioned: [Pg.1390]    [Pg.601]    [Pg.141]    [Pg.1390]    [Pg.601]    [Pg.141]    [Pg.1724]    [Pg.663]    [Pg.706]   
See also in sourсe #XX -- [ Pg.296 ]




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