Thiophosphoryl amide chloride

Bemerkenswert ist ferner die Umsetzung von Diphenylthiophosphinsaure-chlorid mit Di-phenyl-thiophosphinsaure-amid-Kalium- bzw. Lithium-Salz, bei der das stark saure Bis-[diphenyl-thiophosphoryl]-amin (91%) entsteht, das in zwei tautomere Formen vorliegen kann1031 ... 

Primary phosphorothiosulphenamides may be acylated, and with sodium ethoxide they are converted into trialkyl phosphorothionates. Other reactions of phosphorothiosulphenamides include the loss of sulphur upon treatment with sodium, and translocation of the amino-function when treated with thiophosphoryl halides. Treatment of the acyl chloride (71) with ethyleneimine gives an amide which undergoes ready conversion into the isocyanate (72). ... 

Phosphorus trichloride is the starting material used most frequently for the preparation of the esters, amides and anhydrides of phosphoric and phos-phorothioic acids. It can be oxidised to phosphoryl chloride (4) and, heated with sulfur in the presence of a catalyst, to thiophosphoryl chloride (5) (Perot, 1962). 

Thionation of Tertiary Amides. Thiophosphoryl chloride and its V. V-dimethylamide derivatives (eq 1) react with amides at elevated temperature to give thioamides in good yield. The reaction is run in an excess of the thiophosphorus compounds. The most efficient of the thionating agents examined is N,N,N,N-tetramethylamidophosphonothioic chloride. 

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