Thiophene 2- methyl-5-phenyl-, ring synthesis

Thiophene, 2-amino-3-cyano-5-phenyl-synthesis, 4, 888-889 Thiophene, 3-amino-4,5-dihydro-cycloaddition reactions, 4, 848 Thiophene, 2-amino-3-ethoxycarbonyl-ring opening, 4, 73 Thiophene, 2-amino-5-methyl-synthesis, 4, 73 Thiophene, 2-anilino-synthesis, 4, 923-924 Thiophene, aryl-synthesis, 4, 836, 914-916 Thiophene, 2-(arylamino)-3-nitro-synthesis, 4, 892 Thiophene, azido-nitrenes, 4, 818-820 reactions, 4, 818-820 thermal fragmentation, 4, 819-820 Thiophene, 3-azido-4-formyl-reactions... 

Synthesis of Thiophens by Ring-closure Reactions.— The Hinsberg reaction between a-diketones and dialkyl thiodiacetate has been used for the synthesis of a series of 3,4-disubstituted thiophen-2-carboxylates and -2,5-dicarboxylates. The corresponding condensation of ethyl phenyl glyox-ylate and methyl pyruvate with dialkyl thiodiacetate, which yields 3-phenyl-and 3-methyl-4-hydroxythiophen-2,5-dicarboxylates, proceeds through a... 

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