Gold-thiol interactions

The interaction of adsorbed thiol molecules with gold nanoparticles as a function of the mean particle size has also been studied [180]. Monochromated X-ray Photoelectron Spectroscopy (MXPS) measurements showed the attachment of the thiol sulfur headgroup onto the cluster surface leading to a positive BE shift in the Au 4f corelevel. No line width broadening could be observed indicating that the thiol-gold interaction affects the whole... 

Aizawa et al. [14] have immobilized mediator-modified glucose oxidase within micropores of a gold black electrode by self-assembling via the thiol-gold interaction. 

Figure 6. Schematic diagram of the thiol/disulfide equilibrium inside and outside cdls. Gold interacts with different compounds of this system and is expected to...

Shen et al. [16] have recently reported the development of an electrochemical DNAzyme biosensor based on DNA-Au bio-bar code amplification, which provides a platform for fabrication of sensors for analysis of many small molecules, especially for metal ions. For example, a specific DNAzyme for Pb + was immobilized onto an Au electrode surface via a thiol-Au interaction, taking advantage of cataljAic reactions of a DNAzyme upon its binding to Pb + and the use of DNA-Au bio-bar codes to achieve signal enhancement [16]. The presence of gold nanoparticles, enhancing the active surface... 

The simplest structure to understand is that formed when a gold surface is exposed to a simple, linear chain alkanethiol, CH3(CH2) SH. The attraction of thiols for gold has long been appreciated. When a thiol and metallic gold interact, a covalent, Au-S bond forms. As we add more thiol, more absorbs to the surface until it has been passivated—that is, all of the exposed surface area has reacted. Weakly attractive van der Waals interactions induce the alkyl chains to align into two-dimensional... 

Kruger, D., Fuchs, H., Rousseau, R., Marx, D. and Parinello, M. (2001) Interaction of short-chain alkane thiols and thiolates with small gold clusters Adsorption structures and energetics. Journal of Chemical Physics, 115, 4776-4786. 

Self-assembled monolayers (SAMs) [8] The layers are formed by heterologous interaction between reactive groups, such as thiols, and noble metals, such as gold or silver. Since the molecules are selectively adsorbed on these metals, film growth stops after the first monolayer is completed. The molecular aggregation is enthalpy driven, and the final structure is in thermodynamic equilibrium. 

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