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Thioester Transcription factor

Scheme 3 Convergent Synthesis of a Transcription Factor Using both Thioester and Oxime Forming Liga-tionsP4=... Scheme 3 Convergent Synthesis of a Transcription Factor Using both Thioester and Oxime Forming Liga-tionsP4=...
Fukuyama et al. synthesized the alcohol 39 using Evans s chiral auxiliary in the total synthesis of leustroducsin B (37), a potent colony-stimulating factor inducer via NF-kB activation at the transcription level15 (Scheme 2.In). The asymmetric aldol reaction between 38 and the requisite aldehyde proceeded smoothly to afford 39. Protection of the secondary alcohol as the TES ether and removal of the chiral auxiliary with LiSEt furnished the thioester 40. [Pg.66]

See other pages where Thioester Transcription factor is mentioned: [Pg.139]    [Pg.370]    [Pg.1897]    [Pg.629]    [Pg.693]    [Pg.3053]    [Pg.172]    [Pg.284]    [Pg.200]    [Pg.200]   
See also in sourсe #XX -- [ Pg.188 , Pg.192 , Pg.201 , Pg.254 , Pg.269 ]



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