Thin films for tissue engineering applications

Materials and Energy Research Center (MERC), Tehran, Iran 

Louisiana Tech University, Ruston, LA, United States 

Thin Him Coatings for Biomatorials and Biomedical Applications. http //dx.doLoi l0.1016/B978-l-78242-453-6.00008 0 

Thin Film Coatings for Biomaterials and Biomedical Applications 

2 Thin film coating technologies for tissue engineering applications 

---

CPs in different forms like nanofibers and thin films for tissue engineering applications were evaluated by Bendrea et Conducting C-PANl was blended with poly[L-lactide-co-e-caprolactone) (PLCL) and then electrospun to prepare a uniform nanofiber scaffold. This scaffold combined the elastic properties (comes from the PLCL domain) with electrical activity (due to conducting C-PANl) at the nanometer-scale features. It was proved that a nanoscale structure with RANI led to a high pore volume, interconnective pores, a uniform mean fiber diameter, and significantly increased conductivity. ... 

Biomimetic nanocrystalline apatite coatings were deposited on titanium substrates by matrix-assisted pulsed laser evaporation (MAPLE), a technique with potential application in tissue engineering (Visan et al., 2014 Caricato etal., 2014). The targets were prepared from nano-sized, poorly crystalline apatite powders, analogous in composition to mineral bone. For the deposition of thin films, a KrF excimer laser source was used (A = 248 nm,rFWHM < 25 ns). Analyses of the deposited films showed that the structural and chemical nature of the nanocrystalline precursor apatite was preserved. Hence, MAPLE may be a suitable technique for the congruent transfer of a delicate material such as nanohydroxyapatite. 

Thin block copolymer films on surfaces are interesting materials for biomedical and/or biotechnological applications, e.g. tissue engineering. Their chemical versatility allows for the adjustment of desired properties, such as protein repellence or adhesion, and biocompatibility. Mostly, biodegradable PLA- or PCL-based block... 

---