Thiazolidinecarboxylic acid

ANTIBACTERIALAGENTSSYNTTiETIC - SULFONAMIDES] (Vol2) 3-Acetyl-4-thiazolidinecarboxylic acid [8064-47-9]... 

Tharapsutic Function Hepatotherapeutic, choleretic Chemical Name 4-Thiazolidinecarboxylic acid sodium salt Common Name ATC... 

RN 53943-88-7 MF CioH,7N04S2 MW 279.38 EINECS 258-879-3 CN 2-[2-[(2-ethoxy-2-oxoethyl)thio]ethyl]-4-thiazolidinecarboxylic acid... 

The second and minor metabolic pathway consists of the reaction of cyanide with cystine to yield cysteine and B-thiocyanoalanine (Wood and Cooley 1955). The latter is then converted to 2-imino-4-thiazolidinecarboxylic acid and excreted in urine. Cystine has not been used for the purpose of mitigation of cyanide effects because its contribution to detoxification via this pathway is minor. 

Although they are not methods of preparative value in a chemical sense, cysteine, cystine, N-acetylcysteine, 4-thiazolidinecarboxylic acid and cysteine methyl ester when heated in soybean oil at 200 °C produce many sulfur-containing heterocycles among which are found vanishingly small amounts of various 1,2,4-trithianes <76MI 620-01). The reaction is termed the Maillard reaction and is widely employed in laboratories in the flavor industry. 

Internal standard adduct of N-(4-benzoylphenyl)maleimide with (4R)-2-(2-hydro 0 -phenyl)-3-(3-mercaptopropionyl)-4-thiazolidinecarboxylic acid (ISl) 30 min), adduct of N-W-benzoylphenyl)maleimide with thiosalicylic acid (IS2) (14 min) (Prepare adducts as follows. Add 150 mg N-(4-benzoylphenyl)maleimide in 2 mL acetone to 500 [jimoles compound in 2 mL water, add 1 drop triethylamine, let stand at room temperature for 15 min, evaporate to diyness under reduced pressure.)... 

Detection 0.1% Ninhydrin spray reagent, densitometry at 565 or 595 nm. Results values, 0.52 for D-5,5-dimethyl-4-thiazolidinecarboxylic acid and 0.72 for the L-isomer Figure 3.4. 

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