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Some 30 years ago Christian Anfinsens groundbreaking work on the refolding of bovine pancreatic ribonuclease conclusively demonstrated that the information necessary to specify the three-dimensional structure of a folded protein in general is completely specified in the protein s amino acid sequence. Experimentally, the thermodynamic hypothesis of protein folding is now well supported. It states that the native... [Pg.2168]

See other pages where Thermodynamic hypothesis, of protein folding is mentioned: [Pg.289] [Pg.126] [Pg.369]