Thermoanerobacter ethanolicus

Encapsulation of W110A mutant of Thermoanerobacter ethanolicus alcoho dehydrogenase in sol-gel for asymmetric reduction of ketones [20]. 

Organic Solvents Organic solvents have been used for the reaction by oxidoreductase to solubilize hydro-phobic substrates, to construct a two-layer system using hydrophobic solvents to reduce the concentration of toxic substrate and product around enzymes in an aqueous layer, and to simplify the work-up procedure. Water miscible and immiscible solvents have been used. For example, sol-gel-encapsulated alcohol dehydrogenase (WHOA mutant of Thermoanerobacter ethanolicus) was used for asymmetric reduction of 4-phenyl-2-butanone to (5)-4-phenyl-2-butanol in hexane. ... 

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See also in sourсe #XX -- [ , ]

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