Therapy for bacterial infection

Rybak Ml, McGrath BJ. Combination antimicrobial therapy for bacterial infections Guidelines for the clinician. Drugs 1996 52 390-405. 

These alarming deficiencies in therapy for bacterial infections undoubtedly influenced Fleming in his choice of research area when he returned to St Mary s in January 1919. It is unclear as to how he discovered that nasal mucus had antibacterial properties but this line of investigation led to more important work with other body secretions and, in particular, with tears. The so-called tear antiseptic was obtained from volunteers who had lemon juice instilled into their eyes, and proved to be reasonably potent. This same antibacterial agent was subsequently (in January 1922) shown to be present in egg white and this became the primary source of what was eventually christened lysozyme. In his first paper on lysozyme (in Proceedings of the Royal Society, 1922, B, vol. 93, 306), Fleming reported that about three-quarters of the airborne bacteria he had... 

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See also in sourсe #XX -- [ , ]

See also in sourсe #XX -- [ ]

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