Therapeutic potential hemorrhagic effect

In the iliac venous thrombosis model system six animals were studied with good lysis observed venographically in five (23). Figure 2 presents representative venograms illustrating the effectiveness of thrombolysis induced by selective application of natural fibrolase. No toxicity, little or no hemorrhaging, and no evidence of other side effects were observed in the animals studied. These studies again demonstrate the favorable therapeutic potential of native fibrolase. 

A metaanalysis indicated that EGb 761 (an extract of ginkgo biloba) may have some therapeutic effect at doses of 120 to 240 mg of the standard leaf extract twice daily. Because of limited efficacy data, the potential for adverse effects (e.g., nausea, vomiting, diarrhea, headache, dizziness, weakness, and hemorrhage), and the poor standardization of herbal products, it is recommended that ginkgo biloba be used only with caution. 

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