The Structure and Reactivity of Organophosphorus Compounds

Decaborane-14 and Its Derivatives M. Frederick Hawthorne The Structure and Reactivity of Organophosphorus Compounds R. F. Hudson... 

Hudson, R. F., Pure Appl. Client., 1964, 9, 371 Adv. Inorg. Chem. Radiochem., 1964, 5, 347 (bonding, structure and reactivity of organophosphorus compounds the latter reference also contains discussion of dn—pit bonding). 

Model compounds (simulants) are often used to estimate the reactivity of organophosphorus pesticides and warfare agents toward potential remediation technologies because of their availability and ease of handling [5-18]. The structures of select organophosphorus pesticides, chemical warfare agents, and model compounds (simulants) are presented in Fig. 1. 

For sometime, phosphinidines, monovalent organophosphorus species with the general formulation (R-P), have been postulated as reactive intermediates in the thermal and photochemical decomposition of several types of stable organophosphorus compounds. While not isolated as stable molecules, these monovalent species can be inferred on the basis of the isolation of products whose structures can be derived rationally from the postulation of such species, as well as on the mass spectra of the transient species themselves. We may view phosphinidines as the phosphorus analogues of nitrenes (R-N), highly reactive monovalent nitrogen species formed as transient intermediates in the thermal decomposition of azides and in the a-elimination reaction of A-tosylates. 

Jokanovic, M., Prostran, M., 2009. Pyridinium oximes as cholinesterase reactivators. Structure-activity relationship and efficacy in the treatment of poisoning with organophosphorus compounds. Curr. Med. Chem. 16, 2177-2188. 

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