The Reovirus Replicative Cycle

The reovirus replicative cycle has been the subject of several recent, extensive reviews (Zarbl and Millward, 1983 Shatkin and Kozak, 1983 Silverstein et al., 1976). For the purposes of this chapter, the reovirus multiplication cycle will be reviewed briefly. The reader is referred to the aforementioned reviews for further details. 

Reovirus Genetics and the Genetic Approach to the Analysis of Reovirus Cytopathogenicity 

Studies with reoviruses type 2 and 3 have shown that both viruses alter host-cell macromolecular synthesis. Type 1 has not been reported to significantly alter host-cell metabolism. 

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