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The prediction results with Kyte-Doolittle preference functions

The prediction results with Kyte-Doolittle preference functions [Pg.422]

Full details of prediction results for each of 168 reference membrane proteins are enclosed in the Supplementary Material (Table IV). We used cross-validation (5-fold, Methods) and the KYTDO scale ( 1). All of 168 proteins were correctly predicted as membrane proteins having at least one transmembrane segment. With 100% correct transmembrane topology 130 proteins were predicted. A total of 631 transmembrane helices were correctly predicted out of a total number of 662 expected transmembrane segments. Only 36 TMH were overpredicted and 31 underpredicted. Of individual residues in TMH configuration 12273 out of 14374 were correctly predicted, 2033 overpredicted and 2101 underpredicted. The performance parameters (Methods) are then Aj = 0.712, = 95.3%, [Pg.422]

Complete prediction results for the gef ecoli protein by using the Kyte-Doolittle hydropathy [Pg.422]




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Doolittle

Functional prediction

Kyte-Doolittle

Predicting function

The results

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