The phenomenon of segregative phase separation — simple coacervation

The Phenomenon of Segregative Phase Separation — Simple Coacervation  

The phenomenon was called simple coacervation by Bungenberg de Jong (1949) in order to distinguish it from complex coacervation where both polymers are concentrated in the same solvent-depleted phase. The phenomenon of simple coacervation in aqueous food biopolymer systems has attracted considerable interest for many years. This is because of the perception of the potential of these phase-separated biopolymer 

Theoretical treatments of simple coacervation based on the statistical thermodynamics of polymer solutions have been set out by Scott (1949), Tanford (1961), Zeman and Patterson (1972), and Hsu and Prausnitz (1974). These treatments have shown that the main molecular factors affecting the phenomenon are  

For purposes of illustration in what follows, we consider the cases of various specific biopolymer mixtures demonstrating the roles of different thermodynamic parameters in determining the tendency towards phase separation. The deciding role of a greater positive value of Ay is indicated for mixtures in which there is a small difference in thermodynamic affinities of the two biopolymers for the solvent, AA2 = A - Au. A pair 

Another pair of systems of this type are mixtures (5) and (6)  

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