The Nature and Properties Desired of Protected Amino Acids

1 THE NATURE AND PROPERTIES DESIRED OF PROTECTED AMINO ACIDS 

FIGURE 3.1 Functional groups and the nature of the moieties used for their protection. Protectors incorporate the alkyl of an alcohol. 

Benzyl alcohol 9-Fluorenylmethanol rerr-Butyl alcohol PhCH2OH, BzlOH C9H9CH2OH, FmOH (CH3)3COH, tBuOH 

Esters -C02Bzl, -COotBu, -C02Fm Ethers OBzl, OtBu, OFm N-Substituents BzlOCO- = benzyloxycarbonyl = Cbz or Z 

FIGURE 3.2 The alcohols from which protectors are derived, and their abbreviated designations. 

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