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The Methylene Group Method of Korenman, Gurevich, and Kulagina

The Methylene Group Method of Korenman, Gurevich, and Kulagina [Pg.156]

Korenman et al. [45] studied the solvent-water partition coefficients Ksv/ of ethylamine, n-propylamine, and n-butylamine at 20°C. Based on the data for these amines with a short, linear alkyl chain, the contributions to the logarithm of the solvent-water partition coefficients were found to be constant among particular solvent classes. The contribution values are shown in Table 13.4.1. Accordingly, A log K0VI for CH2 is 0.50. [Pg.156]




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Group method

Korenman

Kulagina

Methylene group

Of methylene

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