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The Mechanistic Interpretation of PET

Given the importance of ET this step has been comprehensively studied and a number of sophisticated theories developed to model it. Most hinge on the seminal work by Marcus, which was recognised in 1992 with the award of the Nobel prize in chemistry.  [Pg.52]

For further information and alternative mechanistic interpretations of PET, the reader is directed to several pathways that have been lucidly described [Pg.53]

While elucidating the precise nature of the amine base boronic acid (N-B) interaction has been debated (Section 4.9), it is clear that an interaction does exist and it provides two distinct advantages. [Pg.53]

The first, proposed by WulflF, is that the interaction between a boronic acid and proximal amine lowers the p Tg of the boronic acid. This effect is sufficient so as to allow binding to occur at neutral, i.e., physiological, pH. [Pg.53]

Kijima has developed an on—off PET system 79, which behaves in oppo- [Pg.55]


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