The Immune System and Immunotoxicology

Hit and Lead Projiling. Edited by Bernard Faller and Laszlo Urban Copyright 2009 WILEY-VCH Verlag GmbH Co. KGaA, Weinheim ISBN 978-3-527-32331-9 

8-Tetrachlorodibenzo-p-dioxm Thymus atrophy (rat, mouse, guinea pig) 

Lead acetate/lead nitrate Increased susceptibility for infection (rat, mouse) 

Cadmium cbloride Reduced antibody responses (mouse, rabbit) 

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Immunotoxicology is the study of the adverse health effects of xenobi-otics on the immune system. A thorough review of the immune system and immunotoxicology is beyond the scope of this book. The following is a brief outline. The reader is referred to the literature referenced for good introductions to this topicJ19 21l... 

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