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The GeneSwitch Inovio Biomedical System for Ligand-Dependent Transgene Expression

The GeneSwitch (Inovio Biomedical) System for Ligand-Dependent Transgene Expression [Pg.237]

Expression of the therapeutic protein is enhanced by electroporation - the application of a small amount of electricity at the site of injection for a few milliseconds. This high-intensity electric field induces temporary and reversible breakdown of the plasma membrane allowing plasmids and other molecules to gain intracellular access [110]. This plasmid-based PA-inducible transgene regulating [Pg.237]




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Biomedical systems

Expression for

Expression systems

Ligand-dependent transgene expression

Systems dependence

The Ligands

Transgene, expression

Transgenic expression

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