The Effect of Fluorine Substituents on Carbon Chemical Shifts

THE EFFECT OF FLUORINE SUBSTITUENTS ON CARBON CHEMICAL SHIFTS 

Carbon NMR has been considered an essential characterization tool in spite of the fact that its major isotope, the 12C nucleus, is NMR inactive. In spite of its low natural abundance (1.1%) and its low magnetic moment, which lead to a significantly low overall sensitivity relative to 

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