Tetrahydro-2-furancarboxylic acid

C 7H,203 5675-70-7) see Bisantrene (R)-(-i)-tetrahydrofuran-2-carboxylic acid (CjHgOj 87392-05-0) see Faropenem sodium ( )-tetrahydrofuran-2-carboxylic acid (CjHgOg 16874-33-2) see Alfuzosin Faropenem sodium tetrahydro-2-furancarboxylic acid anhydride with ethyl hydrogen carbonate (CgHijO, 167391-50-6) see Alfuzosin... 

C5H80 3,4-dihydro-2H-pyran 110-87-2 359.15 30 534 1,2 4934 C5H803 tetrahydro-2-furancarboxylic acid 16874-33-2 464.30 40.465 2... 

Propenyl)-1,3-dithiane, after lithiation and addition of zinc chloride, reacts with ethyl 2-oxopropanoate to give preferentially the. vvn-adduct37, which is an intermediate in the synthesis of racemic /ra .s-tetrahydro-2,3-dimethyl-5-oxo-2-furancarboxylic acid. It is assumed, that the ethoxycarbonyl group is brought to a pseudoaxial position in the cyclic transition state by the chelating zinc cation. 

Terebic acid Tetrahydro-2,2-dimethyl-6-oxo-3-furancarboxylic acid C7H10O4 79-91-4 168.162 cry 176 0.816 si HgO s FtOH... 

A 50-mL stainless autoclave were charged with 328 mg methyl benzoylformate (2 mmol), 70 mg P(4-CF3C6H4)3 (0.15 mmol), 6 mL toluene, and 32 mg Ru3(CO)i2 (0.05 mmol). After the system was flushed with 10 atm ethylene three times, it was pressurized with ethylene to 3 atm and then with carbon monoxide to additional 5 atm. Then the autoclave was immersed in an oil bath at 160°C. After 20 h, it was removed from the oil bath and allowed to cool for 1 h. The gases were then released. The contents were transferred to a round-bottomed flask with toluene, and the volatiles were removed in vacuo. The residue was subjected to column chromatography on a silica gel (eluent, hexane/EtOAc, 5 1) to give 413 mg tetrahydro-5-oxo-2-phenyl-2-furancarboxylic acid methyl ester as a colorless solid, in a yield of 94%. Purification by bulb-to-bulb distillation afforded the analytically pure product, m.p. 54—56°C, Rf = 0.34 (hexane/EtOAc, 5 1). 

Tetrahydro-4-methyl-5-oxo-2-undecyl-3-furancarboxylic acid, see N-OOOOl Tetrahydro-2-( 1,7-nonadiene-3,5-diynyl)-2//-pyran-3-ol, T-00081 Tetrahydro-2-nonyl-3-pyranol, T-00082 Tetrahydro-2-(2-oxobut-3-ynylidene)-6-pentylpyran, fee E-00054 Tctrahydro-2-oxo-5-undecyl-3-furanacetic acid, fee A-OOOOl... 

ZaR AR, lS,%aR -Tetrahydro-7-hydroxy-2,2-dimethyl-4,7-methano-l, 3-dioxolo[4,5-c]oxepin-6(4//)-one, Q-10 Tetrahydro-3-hydroxy-5-hydroxymethyl-3-furancarboxylic acid, T-26 2,3,3a, 9a-Tetrahydro-3-hydroxy-6-imino-6/ -furo[2, 3 4,5]oxazolo[3,2-a]-pyrimidine-2-methanol, C-170 Tetrahydro-5-hydroxy-3-methylene-2-furanmethanol, D-629 7,8,9,10-Tetrahydro-8-hydroxy-3-methyl-6,9-epoxy-2ff,6ff-pyrimido[2,l-6]-[l,3]oxazocin-2-one, A-715 Tetrahydro-2-hydroxy-6-methylpyran, H-144 Tetrahydro-2-(hydroxymethyl)pyran, T- ... 

Tetra-O-acetyl-p-D-galactopyranosylethene, A-600 Tetrahydro-3-hydroxy-5-hydroxymethyl-3-furancarboxylic acid, T-26 Trianbydroallitol, T-160... 

Tetra-O -beiizoyl-3-deoxy-p-D-e 7i/iro -hex-2-nlopyranose, D-219 Tetrahydro-3-hydroxy-5-hydroxymethyl-3-furancarboxylic acid, T-26 Tetrahydro-2/7-pyran-2,3-diol Q.BS, iRSyfomr. 2-Me ether, 3-Ac, T-28 Tetrahydro-2/7-pyran-2,3-diol Q.RS, iRSyform 2-Me ether, T-28... 

Terebic acid Tetrahydro-2,2-dimethyl-5- C7H o04 oxo-3-furancarboxylic acid 79-91-4 158.152 cry 175 0.815 si HjO s EtOH... 

Axially chiral carboxylic acids such as [2] and [3] can be used to prepare diastereoisomers of secondary alcohols. The NMR spectra of the diastereoisomers show enantiomeric resolution and it is possible to assign absolute configurations. Monocyclic, chiral carboxylic acid compounds such as tetrahydro-5-oxo-2-furancarboxylic acid and 2,2-diphenylcyclo-propane-carboxylic acid have been used to derivatize secondary alcohols for the purpose of enantiomeric resolution. Similarly, bicyclic derivatizing agents such as camphanic acid, camphanic acid chloride, or camphor sulfonyl chloride have been used to derivatize amines or alcohols to their respective amides or esters for the purpose of enantiomeric resolution. 

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