Tetracyclines pharmacologic properties

Nakagawa, S., Massie, B. and Hawley, R.G. (2001) Tetracycline-regulatable adenovirus vectors pharmacologic properties and clinical potential. EurJ. Pharm. Sci., 13, 53-60. 

The causes and significance of drag interactions are multifaceted and can affect the processes by which pharmacologically active entities are absorbed, distributed, metabolized, and excreted (26). An enhanced or diminished modulation of the pharmacologic properties of a drag by another entitity may be harmful (administration of tetracycline with an antacid that contains divalent or trivalent... 

Various parts of M. oleifera are identified for innumerable pharmacological properties viz. antimicrobial activity (12, 134). The juice from the leaves and stem bark of M. oleifera inhibit Staphylococcus aureus but not Escherichia coli (50). The fresh leaf juice inhibits the growth of pathogenic Pseudomonas aeruginosa and Staphylococcus aureus (21, 143). The bark extract possesses anti-fungal and anti-tubercular activity (50). Niaziridin rich fraction of M. oleifera pods enhances the bioactivity of commonly used antibiotics such as rifampicin, tetracycline and ampicillin against gram(+) and (-) bacteria (37). 

---