Tetrachlorodibenzodioxin receptor

Abbreviations. AhR, aromatic hydrocarbon receptor TCDD, tetrachlorodibenzodioxin PXR, pregnenolone-16a-nitrile-X-receptor PCN, pregnenolone-16a-nitrile CAR, constitutive androstane receptor MC, methylcholanthrene PPARa, peroxisome proliferated-activated receptor-a FXR, famesoid-X-receptor LXR, liver-X-receptor RXR, retinod-X-receptor 5-HETE, 5-OH-eicosatetraenoic acid LTB4, leukotriene B4 13-HODE, hydroxyoctadecadienoic acid DMXAA, dimethylxan-thenone-4-acetic acid. [Pg.133]

Whereas three or more or//io-chlorines block rotation about the ring-connecting bond, congeners with none, or only one, or//io-chlorine can relatively easily achieve a planar configuration (colloquially referred to as coplanars ) and may behave as isosteres (compounds with similar shape, functionality, and polarity) to 2,3,7,8 — tetrachlorodibenzodioxin (TCDD). These bind significantly to the dioxin receptor, and meas-... [Pg.437]

AhR activators in humans (aromatic hydrocarbon receptor)-tetrachlorodibenzodioxin (TCDD), (3-naphthoflavone, 3-methylcloranthrene. [Pg.53]

In addition to these reviews, Hansch analyses for binding affinities to the P-adrenergic receptor [738, 739], benzodiazepine receptor [740], tetrachlorodibenzodioxin (TCDD) receptor [741, 742], dopamine receptor [743], and estrogen receptor [744] as well as for... [Pg.123]

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