1.1.2.3- Tetrachloro-propene

Tetrachloro propene triallate Tetrachloro sulfenyl chloride captafol... 

Neudecker, T. Henschler, D. (1986) Mutagenicity of chloroolefms in the Salmonellalvaaawaa.-lian microsome test. III. Metabolic activation of the allylic chloropropenes allyl chloride, 1,3-dichloropropene, 2,3-dichloro-l-propene, 1,2,3-trichloropropene, l,l,2,3-tetrachloro-2-pro-pene and hexachloropropene by S9 mix via two different metabolic pathways. Mutat. Res., 170, 1-9... 

Under cocondensation conditions, propene was reported to react with dichlorosilylene to form tetrachloro-l,4-disilacyclohexane derivatives (96, 103). 

Smith was granted a patent (30) covering a continnons process for producing cls-trans 1,2,3-trichloropropene through chlorination of mixtures of 2-chloropropene and 2,3-dichloropropene In vapor phase under chlorine substitution conditions. The addition of chlorine to cis-trans 1,2,3-trichloropropene furnished 1,1,2,2,3-pentachloropro-pane in 74% yield. The dehydrochlorlnatlon of this Intermediate with a base afforded 1,1,2,3-tetrachloro-l-propene (31). 

Smith was granted two patents (32-33) covering a process for preparing 1,1,2,3-tetrachloro-l-propene from 1,2,3-trlchloropropane. In addition, 1,2,2,3-tetrachloropropane was obtained as a by-product. 

In conclusion, the intermediate required for the synthesis of Vegadex, Avadex, and Avadex BW were all derived from 1,2,3-trichloropropane which became available by the distillation of Shell s still bottoms. All intermediates except 1,1,2,3-tetrachloro-l-propene are now available in commercial quantities from Dow Chemical Co. 

In 1968, Tobey and Law reported on the intriguing reaction of furan, substituted furans, and cyclopentadiene with both tetrachloro- and tetrabromocyclo-propene (TBCP). The two unsaturated systems reacted smoothly to directly produce cycloheptanoid systems, the products of a formal [4-i- 3]-cycloaddition reaction. The authors proposed in their early manuscripts that the tetrahalocy-clopropenes underwent an initial thermal Diels-Alder cycloaddition to produce the cyclopropyl norbornene derivatives la and lb (Figure 2). However, these workers were unable to isolate or characterize the primary cycloadducts and instead observed a product which had spontaneously rearranged by way of a halogen atom migration to yield the bicyclo[3.2.1]octadiene nucleus 2a and 2b. 

CA Index Name l//-Benzimidazolium, 5,6-dichloro-2-[3-(5,6-dichloro-l,3-diethyl-l,3-dihydro-2//-benzimida-zol-2-ylidene)-l-propen-l-yl]-l,3-diethyl-, iodide (1 1) Other Names l//-Benzimidazolium, 5,6-dichloro-2-[3-(5,6-dichloro-l,3-diethyl-l,3-dihydro-2//-benzimida-zol-2-ylidene)-l-propenyl]-1,3-diethyl-, iodide 5,6-Di-chloro-2-[3-(5,6-dichloro-l,3-diethyl-2-benzimidazoli-nylidene)propenyl] -1,3 -diethylbenzimidazolium iodide Benzimidazolium, 5,6-dichloro-2-[3-(5,6-dichloro-l,3-diethyl-2-benzimidazolinylidene)propenyl]-1,3-diethyl-, iodide Benzimidazolocarbocyanine iodide, 5,5, 6,6 -tet-rachloro-l,l, 3,3 -tetraethyl- Imidacarbocyanine iodide, 1, l, 3,3 -tetraethyl-5,5, 6,6 -tetrachloro- 1, l, 3,3 -Tetra-ethyl-5,5, 6,6 -tetrachlorobenziimdazolocarbocyanine iodide 1, l, 3,3 -Tetraethyl-5,5, 6,6 -tetrachloroimidacar-bocyanine iodide 5,5, 6,6 -Tetrachloro-l,l, 3,3 -tetra-ethylbenzimidazolocarbocyanine iodide Bis(5,6-di-chloro-1,3-diethyl-2-benziimdazole)trimethinecyanine iodide CBIC2 JC 1 NK 1420 Merck Index Number Not listed Chemical/Dye Class Cyanine Molecular Formula C25H27CI4IN4... 

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