Terpyridine Complex Amino Acid

Kwong, H.-L., Wonga, W.-L., Lee, Ch-.S., Yeung, Ch.-T., Teng, P.-F. (2009). Zinc(II) complex of terpyridine-crown macrocycle A new motif in fluorescence sensing of zwitterionic amino acids. Inorg. Chem. Commun., 12, pp. 815-818, ISSN 1387-7003... 

Figure 18 Selected terpyridine complexes that are used for the recognition of free amino acids and peptides.

A competitive assay (indicator displacement assay, IDA) was reported by Anslyn using the Zn(II) complex 49 shown in Figure 21. This 2,2 6,2"-terpyridine complex forms a chemosensing ensemble with pyrocatechol violet because of the ability of the dye to chelate the Zn(II) cation. On addition of a series of unprotected amino acids to a solution of the chemosensing ensemble, the release of the dye was visually verified and spectroscopically measured (1 1... 

A chiral zinc(ll) complex cmitaining a terpyridine fluorophore with C2 symmetry 13 (Fig. 5c) and a crown ether residue was recently reported as fluorescent sensor for amino acids, using the metal ion and the crown ether unit as binding sites... 

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