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Temperature-responsive gene delivery

The properties associated with the amphiphilic monomer units are strongly exemplified in thermosensitive water-soluble polymers, typical examples of which are shown in Scheme 5. Thermosensitive polymers possess a lower critical solution temperature (LCST) in water solutions. Due to their sharp response to temperature variation, they are widely used in various scientific and technological applications. Drug and gene delivery [1-3], chromatographic [9,10], membrane technology [11,12], and catalyst immobiliza-... [Pg.188]

Yokoyama, M. (2002) Gene Delivery Using Temperature-Responsive Polymeric Carriers, Drug Disc. Today, 7, 426-32. [Pg.87]

Haladjova, E., Toncheva-Moncheva, N., Apostolova, M.D., Trzebicka, B., Dworak, A., Petrov, P, et al, 2014. Polymeric nanoparticle engineering from temperature-responsive polymer mesoglobules to gene delivery systems. Biomacromolecules 15 (12), 4377 395. http // dx.doi.org/10.1021/bm501194g. [Pg.92]

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Gene delivery

Temperature response

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