Telitoxicum

Telitoxicum minutiflorum (Diels) Mold. T. peruvianum Mold. 

An interesting and unusual aporphinoid obtained from Telitoxicum peruvianum (Menispermaceae) is the reddish-brown telazoline, which possesses two nitrogen atoms. The tentative structure (62) has been advanced for this compound.73... 

Oxocrebanine (63) is a new natural oxoaporphine, obtained from Stephania sasakii.4 Oxoanolobine (64), another new oxoaporphine, was found in Guatteria melosma12 and Telitoxicum peruvianum.73... 

A new azafluoranthene is telitoxine (75), found together with the known nor-rufescine in Telitoxicum peruvianum.73... 

Killmer, L., Vogt, F. G., Freyer, A. J., Menachery, M. D. Adelman, C. M. (2003). Lakshminine, a New Rare Oxoisoaporphine Alkaloid from Sciadotenia toxifera, and Structural Revisions of Telazoline and Teladiazoline, Two Related Oxoaporphines from Telitoxicum peruvianum and T. glaziovii. J. Nat. Prod., 66, 115-118. 

Alkaloid from woody stems of Telitoxicum krukovii (Menispermaceae). Blood red needles (MeOH/CHCl3). Mp 275-277°. Artifact. 

Bameby et Krukoff, Sciadotenia Miers, and Telitoxicum Mold. 

Menachery MD, Cava MP (1981) The alkaloids of Telitoxicum peruvianum. J Nat Prod 44 320-323... 

Abuta,Anisocycla, Chasmanthera, Cissampelos, Limacia, Limaciopsis, Pachygone, Pycnarrhena, Rhigiocarya, Sinomenium, Sephania, Telitoxicum, Triclisia... 

Strychnos is the only genus of the Loganiaceae whose species are involved in the making of curare (Table 1.1). On the other hand, representatives of several genera of Menispermaceae have been utilized—not only species of Chondrodendron and Curarea, which are known to be active, but also species of Sciadotenia, Abuta, Anomospermum, Telitoxicum, as well as Cissampelos (Table 1.2) there is a dearth of information about the activity of these latter genera. 

Strychnos and Curarea supplied about 85% of the plant material in the case of the Tikuna curare and about 78% in the case of the Canelo Quechua product. It may well be that the other Menispermaceae employed— the Sciadotenia, Telitoxicum, and Cissampelos—contributed additional active substances, but with the current incomplete knowledge of their alkaloids the point remains uncertain (cf. Sections 1.4.6.3,1.4.6.8,1.4.6.9). 

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