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Telavancin Antibiotic

Theravance / Astellas Pharma Arbelic, Vibativ 372151-71-8 (free base) 380636-75-9 (hydrochloride) 1729.11 [Pg.525]

Telavancin (28 Vibativ ) Vancomycin (27) Antibiotic Semi-synthetic NP Microbial Antibacterial Inhibits bacterial cell wall synhiesis 304-311... [Pg.25]

Leadbetter MR, Adams SM, Bazzini B, Fatheree PR, Karr DE, Krause KM, Lam BM, Linsell MS, Nodwell MB, Pace JL, Quasi K, Shaw JP, Soriano E, Trapp SG Villena JD, Wu TX, Christensen BG Judice JK. (2004) Hydrophobic vancomycin derivatives with improved ADME properties Discovery of telavancin (TD-6424). J Antibiot 57 326-336. [Pg.139]

Dalbavancin, oritavancin and telavancin are a new class of semi-synthetic glycopeptide antibiotics and are now under clinical trial. These antibiotics have important side chains and exhibit potent activity against gram-positive bacteria, including MRSA and VRE (Fig. 14, Tables 3,4). [Pg.705]

Telavancin is a new semisynthetic glycopeptide antibiotic with rapid bactericidal activity for gram-positive bacteria, which is mediated by a pair of biochemically distinct mechanisms inhibition of bacterial membrane phospholipids synthesis and inhibition of bacterial cell wall... [Pg.705]

See other pages where Telavancin Antibiotic is mentioned: [Pg.525]    [Pg.525]    [Pg.475]    [Pg.526]    [Pg.527]    [Pg.16]    [Pg.114]    [Pg.627]    [Pg.278]   
See also in sourсe #XX -- [ Pg.705 ]



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