Task-specific ionic liquids supported synthesis

Keywords Supported catalysts Supported reagents Supported synthesis Task specific ionic liquids Task specific onium salts... 

A novel and efficient task-specific ionic liquid synthesis of Biginelli compounds has been developed. Ionic liquid phase-bound acetoacetate reacted with urea or thiourea and various aldehydes in the presence of a cheap catalyst to afford ionic liquid phases supported 3,4-dihydropyrimidine-2-(thi)ones. The desired 3,4-dihydropy-rimidine-2-(thi)ones were easily cleaved from the ionic liquid phase by transesteri-flcation under mild conditions in good yields and high purity. The task-specific ionic liquid technology represents an attractive alternative to the classical solid- and... 

A new strategy for the synthesis of polyhydroquinolines from task-specific ionic liquids (TSIL) as a soluble support was developed. The preparation of the polyhydroquinolines by a three-component reaction was achieved by using ionic liquid... 

Some potential applications for TSILs have been briefly highlighted in Figs. 2.3-3 and 2.3-4. Many more examples can be found throughout this book. The reader interested in catalytic applications of TSILs is referred to Chapter 5, Section 5.3 for more details. Section 5.5 describes explicitly the role of task-specific ionic liquids as new liquid supports in combinatorial syntheses. This section also provides more details on the synthetic procedures leading to the specific functionalized ionic liquids that have turned out to be particularly suitable for this purpose. While Section 5.6 expands on the role of alkoxysilyl functionalized ionic liquids for surface modification in the preparation of supported ionic liquid phase (SILP) catalysts, Section 6.3 is devoted to the synthesis of nanoparticles and nanostructures in which TSILs often play a decisive role as templates or particle stabilizing agents. 

Task-specific Ionic Liquids as New Phases for Supported Organic Synthesis... 

Here we provide a comprehensive review of new task-specific ionic liquids (TSILs) and binary task-specific ionic liquids (BTSILs) as functional ionic liquids designed as alternate soluble supports for supported organic synthesis (SPOS) and combinatorial chemistry. The applications of these supports are based mainly on imida-zolium, ammonium and pyridinium salts. The versatility of the supports has been... 

Task-specific Ionic Liquids as New Phases for Supported Organic Synthesis 501 Table 5.5-5 Loading capacity of the onium salts [A-(CH2) OH]p(]... 

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