Tartronaldehydic acid

Other work with the lower-carbon sugars and related compounds during the years in Basle included the oxidative cleavage of 3,4-0-isopropylidene-D-mannitol with lead tetraacetate, to produce an acetonated tartaric dialdehyde (with H. Appel), the application of the Strecker synthesis to this dialdehyde and to 2,3-0-isopropylidene-D-glyceraldehyde (with L. Feldman), and studies based on glyoxal hemiacetal and nn-tartronaldehydic acid (with E. Baer and H. Nidecker). 

XXXVIII) per mole, whereas splitting of other bonds—since glycols are attacked faster than hydroxy aldehydes76—will yield three moles of glyoxal per mole, and ultimately six moles of formic acid. Tartronaldehyde probably reacts in the (tautomeric) reductone form XXXIX, which is known67 77 to be oxidized to glyoxylic acid. If about 40 % of compound XXXV is split between C3 and C4, the stoichiometry of the inositol oxidation is accounted for. 

Quantitative determination of ascorbic acid in biological fluids and processed foods is hindered by interference by ferrous, cuprous and stannous ions, phenols, sulphydryl compounds, reductone (LXXIX), reductic acid (LXXVIII) and tartronaldehyde (LXXX). The most commonly used method of estimation is based on the rapid reduction of 2,6-dichlorophenol-indo-phenol ( indophenol ) to its leuco form by ascorbic acid. This method, which Wcisfirst introduced by Tillmanns, Hirsch and Hirsch , involves the titration of an acid extract of the tissue or vitamin with a dilute solution of the dye. 

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