Targets for engineering of brewing yeast

Traits chosen for manipulation in brewing strains fall into the following categories  

Process Increased Increased ethanol yield Overexpression of GUI Cao et al. (2007) 

Beer quality Altered flavour Altered volatile spectrum Reduced hydrogen sulphide Reduced dimethyl sulphide Alcohol acetyltransferase Manipulation of BAP2 to modulate higher alcohols Increased copy number of MET25 gene Removal of dimethyl sulphide oxidase by deletion of MXRl Fujii et al. (1994) Kodama et al. (2(X)1) Qmura, Shibano, Fukui, and Nakatani (1995) Hansen, Braun, Bech, and Gjermansen (2002) 

Novel beers Low or zero alcohol beers Increased glycerol production Manipulation of GDPl Nevoight et al. (2002) 

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