Targeting Different Age Groups

Marcel Dekker, Inc. 270 Madison Avenue. New Yoik, New York 10016 

In healthy adults 18 years of age, total lung deposition (tracheobronchial and pulmonary) does not appear to change with age. 

Models and experimental data indicate that total deposition will be significantly reduced in babies and young children compared to older children and adults. 

This difference suggests that adult doses of aerosolized medications should not be reduced when administered to babies and young children, because the dose that deposits is already significantly reduced as a result of decreased airway diameter and inhalation volume and increased breathing frequency. 

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