Target Site of Penthiopyrad

Penthiopyrad interrupts electron transport in the mitochondrial respiratory chain. As a result of this effect, the fungus cannot produce vital energy in the form of ATP. 

Mitochondria were extracted from mycelia of Rhizoctonia solani, Botrytis cinerea, and Fusarium oxysporum. Succinate-ubiquinone oxidoreductase activity was assayed spectrophotometrically following the method of Miyoshi [3] and the results are listed in Table 3 expressed as Ijq (50% inhibition). 

Penthiopyrad showed high inhibitory activity against the enzyme Complex II derived from not only Rhizoctonia solani but also Botrytis cirterea and Fusarium oxysporum. 

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