Target Proteins by CCT

Whether or not target proteins bound to Type II chaperonins undergo similar cycles of binding and release has been a matter of controversy. On the one hand, CCT-generated tubulin intermediates can be efficiently trapped by the inclusion in the folding reaction of a molar excess of 

Notwithstanding questions regarding the effectiveness of different mutant traps in sequestering cycling intermediates, it is worth sounding a 

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