Target guest compound

If our molecular imprinting is very successful, the k value of the target guest compound alone should be notably increased and those for all other compounds remain unchanged. This polymer clearly remembers... 

A disadvantage of diazo compounds is that they are quite polar, which endows them with a propensity to form dimers in the gas phase, even at concentrations as small as 1 5000. This feature becomes evident after their decomposition, which sometimes leads predominantly to carbene dimers (e.g., pentafulvalene in the case of diazocyclopentadiene" ), or adducts of the target carbene with its diazo precursor, as in the case of methylene, where the main products are CH2=NH and HCN." The problem disappears at very high guest/host ratios, but it is often impractical to achieve these. Fortunately, diazirines are less prone to dimerization in the gas phase. 

Practically motivated, the aim was to develop methods for recovery and determination of amino acids in the context of analytical chemistry and biotechnology. Amino acids are hydrophilic compounds, which therefore are difficult targets for conventional solvent extraction. Extraction to an organic solvent may be enhanced by the addition of lipophilic cationic or anionic extractants, forming extractable complexes with amino acids, or by the use of macrocyclic compounds, which form stable hydrophobic host-guest complexes. The most popular reagents from the latter group are crown... 

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